Melatonin is a hormone produced by the pineal gland located at the center of the brain. The body uses melatonin as a regulator of sleep patterns. Melatonin production is high until adolescence and decreases with age. The main function of melatonin is to regulate the body’s biological clock.
The secretion of melatonin is inhibited during the day and stimulated during the night, the maximum values of melatonin are around 2 or 3 am, hence its other name: the hormone of sleep or the hormone of the dark. Through melatonin, the pineal gland informs the brain about the relative duration of dark hours and light in a 24-hour period that is the daily cycle, and also throughout the year that is seasonality.
Thanks to its lipophilic, melatonin can spread easily through the body, including intracellular membranes, particularly in neurons, hence its ability to act on the central nervous system.
Melatonin is useful for people who suffer from “jet lag” and can also help men and women of a certain age with certain forms of sleep disorders or insomnia. Melatonin acts quickly (about 1/2 hours) and improves sleep quality. Melatonin supplements appear to be more effective in preventing unnecessarily waking up at night.
In a six-week study, with 34 subjects, where 3 mg of melatonin was administered before bedtime was more effective than placebo in relieving insomnia. It has been observed that six months later, in most cases, the sleep of the patients who continued taking melatonin was of good quality. Still researching the different benefits of melatonin has been shown to have in general health.
Melatonin is also recommended for people who suffer from emotional disorders such as stress. In a study on the benefits of melatonin. Melatonin was administered in patients undergoing surgery to reduce their anxiety. Melatonin is also effective in treating depression-associated insomnia.
It was observed that melatonin improves engine performance and jet lag conditions. Researchers in a study published in 2002 have examined the results of nine clinical trials that compared the efficacy of melatonin with placebo and found its efficacy in preventing or reducing jet lag.
The cure with melatonin is more pronounced when traveling eastward through five time zones or more, but it is still measurable if it does not pass through two to four times. It is said that the effect of migraine and some headaches are caused by an alteration of the heart rhythms. Researchers believe that melatonin is useful in these cases.
Some studies suggest that when you buy melatonin uk – the melatonin may alleviate headache and help improve sleep nights in people suffering from this condition. The results of a study conducted in Italy indicate that taking a melatonin supplement at the time of menopause can have anti-aging effects by reducing prolactin levels and the follicle stimulates two hormones that increase in women During this step.
Most women who took melatonin also reported improving their mood or decreased symptoms of depression, unlike the group who took a placebo. Another test indicates that potential cardiovascular benefits associated with the use of melatonin (lowering blood pressure) only affect post-menopausal women with a hormone replacement therapy program.
Melatonin and other treatments
Melatonin is sometimes used to increase the efficacy of conventional treatments, as it is a hormone has an anti-tumor activity, or to minimize the side effects particularly to combat thrombocytopenia can be caused by the Cancer or treatments intended to fight.
The promotion of melatonin helps with tumour regression and increases the survival rate of patients with breast, lung, liver, pancreas, stomach or colon tumours.
In addition, this hormone has been used to reduce the frequency of seizures in epileptic children. Researchers have noticed that people with certain health problems had lower levels of melatonin than healthy people.
Travelers and people who work rotating schedules according to suffer from sleep disturbances that seem to be caused by a change in their levels of melatonin.